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Text File  |  1995-11-09  |  285b  |  3 lines
  1. Fig. 17.11 
  2. Mechanism of action of TSH-R(s). 
  3. TSH and TSH-R antibodies in patients with Graves' disease bind to the extracellular domain of the receptor, and by acting via the receptor-linked G-binding protein stimulate cyclic AMP production and subsequent thyroid hormone synthesis.